Identification of the Neuromuscular Junction Transcriptome of Extraocular Muscle by Laser Capture Microdissection

摘要

Expression patterns of genes at the synapses (or neuromuscular junctions) of extraocular muscles are described by using microarray expression profiling to understand the molecular makeup of the synapses of these small and specialized sets of skeletal muscles. The extraocular muscle synapses expressed genes that are also expressed in limb muscle synapses, but several genes were identified at the same time that showed unique differential regulation patterns compared with limb synapses.